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Discover Supplement-Drug Interactions
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Last Updated: 5 years ago
supplement:
Citicholine
drug:
Levodopa
Research Papers that Mention the Interaction
“It is concluded that the levodopa-saving effect of citicoline could be used to decrease the incidence of side effects and retard the loss of efficacy of levodopa in long-term treatment.”
Citicoline in the treatment of Parkinson's disease.“In a second stage of CDPC treatment, also lasting 30 days, the dose of levodopa was reduced by one-third, and the incidence of dyskinesia dropped to its previous level, but the therapeutic response remained stable.”
“ Citicoline allowed effective reduction of levodopa by up to 50%.”
“The CDP-choline did not modify the apomorphine-induced stimulant effect but potentiated the circling behaviour produced by L-DOPA and amphetamine.”
Circling behaviour in rats with unilateral lesions of the nigrostriatum induced by 6-hydroxydopamine: Changes induced by oral administration of cytidine-5'-diphosphocholine
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