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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
drug:
Citalopram
supplement:
Melatonin
Research Papers that Mention the Interaction
“Further, melatonin onset occurred later under normal room light with citalopram compared to placebo.”
“ResultsA 47% increase in melatonin suppression was observed after administration of an acute dose of citalopram , with all participants showing more suppression after citalopram administration (large effect, d = 1.54).”
The SSRI citalopram increases the sensitivity of the human circadian system to light in an acute dose“If FLU, but not CIT , inhibits liver enzymes involved in the metabolism of MT , different serum MT concentrations should probably ensue.”
“Our results demonstrate that citalopram increases the level of melatonin which negatively regulates GSK-3β and attenuates tau hyperphosphorylation and spatial memory deficit induced by SI in middle-aged rats.”
Citalopram Attenuates Tau Hyperphosphorylation and Spatial Memory Deficit Induced by Social Isolation Rearing in Middle-Aged Rats“Here, we found decreased immobility behavior in mice treated with melatonin (<14–33%) and citalopram (<17–30%).”
“In addition, we investigated the potential antidepressant role of the combination of melatonin and citalopram (MLTCITAL), its type of pharmacological interaction on depressive behavior, and its effect on hippocampal neurogenesis.”
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