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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
drug:
Citalopram
supplement:
Citicholine
Research Papers that Mention the Interaction
“An isobolographic analysis of data was performed, presenting a synergistic interaction between citalopram and citicoline upon the production of anxiolytic effect in non-sensitized and morphine-sensitized mice.”
“Moreover, i.p.co-administration of citalopram (5 and 10 mg/kg) and citicoline (75 mg/kg) induced the anxiolytic effect.”
“co-administration of low doses of citalopram (0.5, 1 and 2.5 mg/kg) and citicoline (25 mg/kg) significantly increased %OAT and %OAE in non-sensitized as well as %OAT in morphine-sensitized mice, indicating an anxiolytic effect.”
Synergistic effect between citalopram and citicoline on anxiolytic effect in non-sensitized and morphine-sensitized mice: An isobologram analysis“Based on the results, it can be concluded that administration of citicoline , as an adjuvant drug, in combination with citalopram , enhanced the effectiveness of selective serotonin reuptake inhibitors (SSRI) drugs for depression treatment.”
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