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Last Updated: 3 months ago

Possible Interaction: Citalopram and Citicholine

supplement:

Citicholine

Research Papers that Mention the Interaction

Based on the results, it can be concluded that administration of citicoline , as an adjuvant drug, in combination with citalopram , enhanced the effectiveness of selective serotonin reuptake inhibitors (SSRI) drugs for depression treatment.
Physiology & Behavior  •  2018  |  View Paper
An isobolographic analysis of data was performed, presenting a synergistic interaction between citalopram and citicoline upon the production of anxiolytic effect in non-sensitized and morphine-sensitized mice.
Moreover, i.p.co-administration of citalopram (5 and 10 mg/kg) and citicoline (75 mg/kg) induced the anxiolytic effect.
co-administration of low doses of citalopram (0.5, 1 and 2.5 mg/kg) and citicoline (25 mg/kg) significantly increased %OAT and %OAE in non-sensitized as well as %OAT in morphine-sensitized mice, indicating an anxiolytic effect.
Brain Research  •  2020  |  View Paper