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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
drug:
Cisplatin
supplement:
Selenate, Sodium
Research Papers that Mention the Interaction
“In addition, sodium selenate , an inhibitor of TRXR, was found to increase the susceptibility to CDDP in the CDDP-resistant cells.”
Possible involvement of thioredoxin reductase as well as thioredoxin in cellular sensitivity to cis-diamminedichloroplatinum (II).“Administration of sodium selenate significantly alleviated the afore-mentioned adverse effects of cisplatin on the fetuses and their placentas so we conclude that sodium selenate as an antioxidant has an effective protective role in cisplatin teratogenic effects.”
Teratogenic effect of cisplatin in rats and the protective role of sodium selenate.
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