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Discover Supplement-Drug Interactions
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Last Updated: 2 years ago
drug:
Cisplatin
supplement:
Scutellaria Baicalensis
Research Papers that Mention the Interaction
“ SB potentiated the anti‐growth effects of cisplatin on OC cells by attenuating the expression of HIF‐1α, ABCG1, and ABCG2.”
“Taken together, the findings suggest that targeting HIF‐1α with SB could be an effective treatment strategy for cancer and SB can improve the sensitivity of cancer cells to cisplatin , which is a major challenge in therapy for ovarian tumors.”
Scutellaria baicalensis targets the hypoxia‐inducible factor‐1α and enhances cisplatin efficacy in ovarian cancer“Autophagy was not induced by neither cisplatin nor SbE. Intriguingly, the combinational treatment of SbE and cisplatin significantly decreased cell viability in CRC.”
“ResultsTreatment of cisplatin or SbE reduced cell viability significantly in CSC and too much lesser extent in CRC.”
“CONCLUSION SB ca n enhance the anti-cancer effect of cis platin. ”
“In the animal experiment, SB improved the loss of murine body weight and gastrocnemius muscle, the elevating BUN level, and the apoptosis of renal tubular cells in mice receiving cisplatin therapy.”
“In this study, we report the synergic effect of SB and cisplatin to Lewis lung carcinoma (LLC) cells, and the ameliorative effect of SB to cisplatin-induced cachexia and acute kidney injury.”
The concurrent treatment of Scutellaria baicalensis Georgi enhances the therapeutic efficacy of cisplatin but also attenuates chemotherapy-induced cachexia and acute kidney injury.
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