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Last Updated: 2 years ago

Possible Interaction: Cisplatin and Rutin

supplement:

Rutin

Research Papers that Mention the Interaction

On the other hand, tGSH and SOD levels were statistically significantly decreased with cisplatin administration and giving rutin concomitantly with cisplatin prevented this decrease.
Cutaneous and ocular toxicology  •  2018  |  View Paper
Two other flavonoids tested, i.e., rutin (3-rhamnosylglucoside of quercetin) and hesperidin [7-b rutinoside of hesperetin (3'-5-3-hydroxy-4-methoxyflavone)] were ineffective both alone and in combination with CDDP.
Anti-cancer drugs  •  1990  |  View Paper
In the rutin plus cisplatin combination-treated mice, all the abnormal tissue architectural features were decreased.
Human & experimental toxicology  •  2020  |  View Paper
Cisplatin treatment increased p-PTEN and decreased p-FOXO3a expression in follicles, which was prevented by 10 mg/kg rutin.
Reproductive toxicology  •  2020  |  View Paper
Rutin co-treatment resulted in reversing cisplatin effect on DNA damage, sperm count, histological and biochemical parameters.
BMC Urology  •  2018  |  View Paper
Rutin pretreatment prevented deteriorative effects induced by cisplatin through a protective mechanism that involved reduction of increased oxidative stress as well as caspase-3, TNF-α and NFκB protein expression levels.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association  •  2011  |  View Paper