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Discover Supplement-Drug Interactions

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Last Updated: 2 years ago

Possible Interaction: Cisplatin and Perillyl Alcohol

Research Papers that Mention the Interaction

Apoptotic mechanistic studies indicated that POH and MJ treatment activated tumor necrosis factor receptor 1 and this was further increased by the addition of cisplatin.
It was also found that mitochondrial membrane potential decreased with POH and MJ treatment; this effect was further enhanced by cisplatin treatment.
POH and MJ treatment (20% decrease in cell viability concentration) enhanced the cytotoxicity for subsequent exposure to cisplatin in MDA-MB-435 and MDA-MB-231 cells.
Anti-cancer drugs  •  2010  |  View Paper