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Discover Supplement-Drug Interactions
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Last Updated: 2 years ago
drug:
Cisplatin
supplement:
Paricalcitol
Research Papers that Mention the Interaction
“VDR agonist paricalcitol could both functionally and histologically attenuate cisplatin induced AKI by decreasing lipid peroxidation (featured phenotype of ferroptosis), biomarker 4-hydroxynonenal (4HNE), and malondialdehyde (MDA), while reversing glutathione peroxidase 4 (GPX4, key regulator of ferroptosis) downregulation.”
VDR activation attenuate cisplatin induced AKI by inhibiting ferroptosis
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