“CONCLUSIONS KL pr etreatment may increase the effects of CDD P on HepG2 cells, by exhibiting cooperative effects on suppression of HepG2 cells.”
“Expression of CKLF1 enhanced significantly in CDDP treated HepG2 cells, and KLT decreased this elevation obviously.”
“Furthermore, we found that ABC drug efflux transporters MDR1, MRP2, and BCRP in CDDP treated HepG2 cells were decreased when pretreated with KLT.”
“RESULTS KL pr etreatment followed by CDD P tr eatment was found to show synergistic effects, which showed by decreased cell viability, migration and invasion ability of HepG2 cells.”