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“Micropuncture studies suggest that cisplatin reduces single-nephron glomerular filtration rate (GFR) and causes a significant backleak of inulin across the renal tubule.”
“ Cisplatin caused dose-dependent declines in the mean inulin clearance values in the rat that were not attenuated with pharmacological doses of pentoxifylline.”
Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association • 1992 | View Paper
“ Inulin clearance was low 4 days after cisplatin.”