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Discover Supplement-Drug Interactions

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Last Updated: 2 years ago

Possible Interaction: Cisplatin and Glucosamine



Research Papers that Mention the Interaction

Our results indicated that glucosamine reduced the proliferation of human ovarian cancer cell lines (A2780) and its cisplatin resistant variant (A2780RCIS) in a dose-dependent manner.
The IC50 values for A2780RCIS cells treated with cisplatin in the presence of different concentrations of GlcN (0, 1, 2 and 3 mM) for 72 h were 44.463 ± 1.603, 35.17 ± 0.025, 22.25 ± 0.018, 17.78 ± 0.012 μM respectively.
European journal of pharmacology  •  2019  |  View Paper
Furthermore, treatment of rats with glucosamine before cisplatin significantly inhibited apoptosis, necrosis and ROS generation in bone marrow cells, and also increased red blood cells count in peripheral blood.
Anti-cancer agents in medicinal chemistry  •  2019  |  View Paper