supp.ai
Discover Supplement-Drug Interactions
Disclaimer: The information contained herein should NOT be used as a substitute for the advice of an appropriately qualified and licensed physician or other health care provider. The tool is not a substitute for the care provided… (more)
Last Updated: 3 years ago
drug:
Cisplatin
supplement:
Glucosamine
Research Papers that Mention the Interaction
“Our results indicated that glucosamine reduced the proliferation of human ovarian cancer cell lines (A2780) and its cisplatin resistant variant (A2780RCIS) in a dose-dependent manner.”
“The IC50 values for A2780RCIS cells treated with cisplatin in the presence of different concentrations of GlcN (0, 1, 2 and 3 mM) for 72 h were 44.463 ± 1.603, 35.17 ± 0.025, 22.25 ± 0.018, 17.78 ± 0.012 μM respectively.”
Glucosamine reverses drug resistance in MRP2 overexpressing ovarian cancer cells.“Furthermore, treatment of rats with glucosamine before cisplatin significantly inhibited apoptosis, necrosis and ROS generation in bone marrow cells, and also increased red blood cells count in peripheral blood.”
Glucosamine Protects Rat Bone Marrow Cells Against Cisplatin-Induced Genotoxicity and Cytotoxicity.
Help us improve supp.ai, we'd love to hear your feedback: Submit Feedback