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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
drug:
Cisplatin
supplement:
Gamma-Linolenic Acid
Research Papers that Mention the Interaction
“In our study, it was noted that 7-1inolenic acid GLA ) and eicosapentaenoic acid (EPA) potentiated the cytotoxicity of anticancer drugs vincristine, cis-platinum , and doxorubicin on human cervical carcinoma cells in vitro by enhancing the uptake of anticancer drugs.”
Reversal of tumor cell drug resistance by essential fatty acids“On the other hand, that of platinating agents such as cisplatin (CDDP) and carboplatin (CBDCA) was inhibited by GLA supplementation.”
“Gamma-linolenic acid GLA ) of the n-6 series and eicosapentaenoic acid (EPA) of the n-3 series potentiated the cytotoxicity of anti-cancer drugs: vincristine, cis-platinum and doxorubicin on human cervical carcinoma (HeLa) cells in vitro.”
Can tumour cell drug resistance be reversed by essential fatty acids and their metabolites?
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