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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
drug:
Cisplatin
supplement:
Formononetin
Research Papers that Mention the Interaction
“Taken together, these findings suggest that formononetin may be a possible option to prevent nephrotoxicity induced by cisplatin during treatment for cervical cancer.”
Inhibition of Intracellular ROS Accumulation by Formononetin Attenuates Cisplatin-Mediated Apoptosis in LLC-PK1 Cells“ Formononetin decreased expression of organic cation transporter 2 (Oct2) and increased the expressions of multidrug resistance‐associated proteins (Mrps), which might result in a decrease accumulation of cisplatin in tubular cells after AKI.”
“Protective effect of formononetin was closely related to the reduction of cisplatin.”
“ Formononetin has an inhibitory effect on cervical cancer tumors similar to that of cisplatin , but the former has smaller side effects, providing data for the clinical use in cervical cancer.”
Effects and significance of formononetin on expression levels of HIF-1α and VEGF in mouse cervical cancer tissue
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