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Discover Supplement-Drug Interactions

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Last Updated: 2 years ago

Possible Interaction: Cisplatin and Ellagic Acid

supplement:

Ellagic Acid

Research Papers that Mention the Interaction

It is notable that a combination of EA and cisplatin , a widely used chemotherapy agent, dramatically enhanced cell death in B16F10 cells, suggesting a promising strategy in chemotherapy.
Genes to cells : devoted to molecular & cellular mechanisms  •  2019  |  View Paper
Ellagic acid nano improved the histopathological changes induced by cisplatin , such as tubular dilatation, necrosis, and degeneration.
Molecules  •  2020  |  View Paper
The administration of EA (10 mg/kg bwt po daily for 6 weeks) significantly ameliorated the toxicity caused by CP (5 mg/kg bwt ip once a week for 4 weeks).
Environmental toxicology  •  2019  |  View Paper
Administration of EA significantly ameliorated the toxicity caused by CP as indicated by improved kidney function tests and reproductive function tests.
Molecular and Cellular Biochemistry  •  2018  |  View Paper
Ellagic acid markedly reduced elevated plasma creatinine, urea and calcium levels and counteracted the deleterious effects of cisplatin on oxidative stress markers.
Basic & clinical pharmacology & toxicology  •  2007  |  View Paper
Pretreatment with resveratrol or ellagic acid 48 h prior to treatment with cisplatin showed a moderate enhancement of cisplatin cytotoxicity in A2780CisR cells (shift factors were 1.6 for ellagic acid and 2.5 for resveratrol).
Journal of Cancer  •  2016  |  View Paper