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Discover Supplement-Drug Interactions

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Last Updated: 3 years ago

Possible Interaction: Cisplatin and Arctigenin

supplement:

Arctigenin

Research Papers that Mention the Interaction

Arctigenin at 100 μM significantly inhibited cell proliferation of cisplatin treated R-SW480 and R-SW620 cells as compared with cells treated with cisplatin alone.
Arctigenin elevates cell apoptosis, up-regulated pro-apoptotic protein cleaved-caspase-3 and caspase-9 expression level in cisplatin treated R-SW480 and R-SW620 cells.
Arctigenin impeded the IC50 of not only cisplatin but also oxaliplatin, doxorubicin and Paclitaxel of R-SW480 and R-SW620 cells.
Biochemical and biophysical research communications  •  2019  |  View Paper
Arctigenin dramatically promoted cisplatin‐induced cell death in cancer cells, indicating that arctigenin enhanced the sensitivity of cancer cells to cisplatin mainly via STAT3 suppression.
Journal of cellular biochemistry  •  2011  |  View Paper