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Discover Supplement-Drug Interactions

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Last Updated: 2 years ago

Possible Interaction: Ciprofloxacin and Serum Albumin, Human

Research Papers that Mention the Interaction

In that, the piperine, Caffeine, indole, isomer of ciprofloxacin N, B, F, and I binds with HSA with binding constant of .5 × 10, 12 × 10, 4.2 × 10, 6.92 × 10, 3.87 × 10, 4.06 × 10, and 2.7 × 10 M, respectively.
Journal of biomolecular structure & dynamics  •  2018  |  View Paper
Furthermore, far-UV CD results show that the binding of CFX leads to change in the helicity of HSA.
Cell Biochemistry and Biophysics  •  2014  |  View Paper
Results of circular dichroism indicated that the secondary structure of HSA was modified with increasing ciprofloxacin concentration.
The titration results indicated that ciprofloxacin quenched the fluorescence intensity of HSA through a static mechanism, but in the presence of Ag nanoparticles of sizes I and II there were two different kinds of interaction behavior.
The journal of physical chemistry. B  •  2012  |  View Paper