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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
drug:
Ciprofloxacin
supplement:
Magnesium
Research Papers that Mention the Interaction
“Antacids that contain magnesium and aluminum salts may reduce the absorption of ciprofloxacin.”
Effects of aluminum and magnesium antacids and ranitidine on the absorption of ciprofloxacin“The concomitant oral administration of magnesium- , aluminium-, or calcium-containing antacids, sucralfate, iron preparations and multivitamins containing zinc significantly reduces the absorption of ciprofloxacin.”
“Cations such as magnesium and aluminum significantly impair the absorption of ciprofloxacin.”
“After reading a patient advisory on a ciprofloxacin patient information sheet that advised avoidance of concomitant administration of ciprofloxacin and magnesium , the patient self-discontinued his pantoprazole as it was a magnesium salt formulation.”
Case report: Proton pump inhibitor drug-related problem in pancreatic cancer patient unmasks pancreatic enzyme insufficiency.“BACKGROUND Concomitant enteral administration of ciprofloxacin with products containing magnesium , aluminum, and calcium (e.g., as enteral feeds) decreases the oral bioavailability of this antibiotic.”
“Simultaneous administration of antacids containing magnesium or aluminium and ciprofloxacin or other quinolones decreases the gastrointestinal absorption of those antibacterial agents.”
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