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Discover Supplement-Drug Interactions
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Last Updated: 2 years ago
drug:
Ciprofloxacin
supplement:
Leucine
Research Papers that Mention the Interaction
“Our results indicated that, in general, ciprofloxacin co-jet-milled with L-leucine at > 0.5% w/w showed a significant higher fine particle fraction (FPF) compared with the ciprofloxacin jet-milled alone.”
Correlations between surface composition and aerosolization of jet-milled dry powder inhaler formulations with pharmaceutical lubricants.“ Ciprofloxacin co‐spray dried with disaccharides and l‐leucine in the mass ratio of 1:1 demonstrated an increase in fine particle fraction (FPF) as compared with the spray dried Ciprofloxacin alone when stored at 20% RH.”
“ l‐Leucine demonstrated aerosolization stability by alleviating crystallization of Ciprofloxacin to some extent and preventing significant change in particle morphology.”
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