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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
drug:
Ciprofloxacin
supplement:
Iron, Dietary
Research Papers that Mention the Interaction
“The release of ciprofloxacin from the cellulose membrane in the presence of aluminum, calcium, or iron ions was slower than that in the absence of these metal ions.”
Impairment of Ciprofloxacin Absorption by Calcium Polycarbophil“The concomitant oral administration of magnesium-, aluminium-, or calcium-containing antacids, sucralfate, iron preparations and multivitamins containing zinc significantly reduces the absorption of ciprofloxacin.”
“In conclusion, concomitant oral iron dosing induced significant changes in the pharmacokinetics/pharmacodynamics of intravenous ciprofloxacin.”
Pharmacokinetic and Pharmacodynamic Interactions between Intravenous Ciprofloxacin and Oral Ferrous Sulfate“HIGHLIGHTS Fe incorporation significantly accelerated the adsorption of CPX on MCM-41.”
“The results showed that the introduction of iron facilitated the absorption quantity for CPX from 20.04 to 83.33 mg g−1 at 120 min of reaction time, which was mainly attributed to surface complexation.”
The Correlation of Adsorption Behavior between Ciprofloxacin Hydrochloride and the Active Sites of Fe-doped MCM-41“This ciprofloxacin-induced tissue iron depletion was more pronounced when it was administered simultaneously with iron , when it was administered for a longer duration (2 months rather than 1 month) and when it was given in higher doses (14 mg/kg per day).”
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