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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
drug:
Ciprofloxacin
supplement:
Guanidines
Research Papers that Mention the Interaction
“Both the basolateral-to-apical and apical-to-basolateral transport of CPFX were inhibited by guanidine , whereas CPFX transport in both directions was not inhibited by TEA, NMN, or cimetidine.”
“ Guanidine and cimetidine inhibited the uptake of CPFX , whereas tetraethylammonium chloride (TEA) and N1-methylnicotinamide (NMN) did not.”
“The basolateral-to-apical transport of CPFX was sensitive to the pH of … medium, and increased in an acidic pH. Enoxacin (ENX) as well as guanidine , inhibited the basolateral-… transport of CPFX , and the inhibitory effect of ENX was sensitive to … pH of the apical side of the monolayers.”
The transport of ciprofloxacin in cultured kidney epithelial cells LLC-PK1.
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