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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
drug:
Ciprofloxacin
supplement:
Gamma-Aminobutyric Acid
Research Papers that Mention the Interaction
“Although the exact mechanism for seizure induction cannot be determined from these cases, potential drug interactions exist, because theophylline, imipenem, and ciprofloxacin are all believed to increase excitation of the central nervous system by inhibition of γ-aminobutyric acid binding to receptors.”
Seizures in Patients Simultaneously Receiving Theophylline and Imipenem or Ciprofloxacin or Metronidazole“In these experiments, ciprofloxacin pre-treatment prevented the inhibitory effects of the ethanol plus GABA combination.”
The effects of ethanol and gamma aminobutyric acid alone and in combination on hepatic regenerative activity in the rat.“ GABA (10 microM)-induced current was inhibited by norfloxacin (NFLX), ciprofloxacin , ENX, and ofloxacin (OFLX) with IC50 of 17, 33, 58, and 280 microM, respectively.”
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