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Discover Supplement-Drug Interactions

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Last Updated: 2 years ago

Possible Interaction: Ciprofloxacin and Ferrous Sulfate

Research Papers that Mention the Interaction

The AUC and peak plasma concentration of ciprofloxacin were reduced by 57% (P < 0.001) and 54% (P < 0.01), respectively, by ferrous sulphate.
We recommend that norfloxacin and ciprofloxacin should not be taken together with ferrous sulphate.
British journal of clinical pharmacology  •  1994  |  View Paper
Peak serum ciprofloxacin concentrations and area under … curve (AUC) were significantly reduced when ciprofloxacin was administered … 300 mg ferrous sulphate (3.0 vs 2.0 mg l-1, P less than 0.05 and 12.3 vs 6.7 mg l-1 h, P less than 0.01, respectively).
British journal of clinical pharmacology  •  1991  |  View Paper
Ferrous sulfate and multivitamins with zinc significantly impaired the absorption of ciprofloxacin.
Antimicrobial Agents and Chemotherapy  •  1989  |  View Paper
The absorption of ciprofloxacin has been reported to be impaired by concomitant administration of ferrous sulphate.
The Journal of pharmacy and pharmacology  •  2000  |  View Paper