“The relative oral bioavailability of ciprofloxacin was calculated as AUC(0- infinity ), Arm B … C/AUC(0- infinity ), Arm A. RESULTS The Cmax and AUC(0- infinity ) of ciprofloxacin were significantly decreased when … with sevelamer hydrochloride or calcium acetate (P < 0.05), and bioequivalence … not achieved for either parameter.”
“The relative oral bioavailability of ciprofloxacin was decreased by 48% with sevelamer hydrochloride and 51% with calcium acetate (P < 0.05).”