“Gastric and duodenal lesion … patients treated with cimetidine 400 mg bd: … (0.5) ( SE ); n = 42) was significantly lower (p less than 0.0122) than in placebo treated patients: 6.1 (0.… = 50) or in patients treated with cimetidine 400 mg at night 7.1 (0.8) (n = 21).”