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Discover Supplement-Drug Interactions

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Last Updated: 3 years ago

Possible Interaction: Cimetidine and Secretin

supplement:

Secretin

Research Papers that Mention the Interaction

Cimetidine treatment significantly promoted the healing of duodenal ulcers and gastric ulcers with extensive acid secreting areas when compared with placebo, but not of the gastric ulcers without extensive acid secreting areas.
Gut  •  1986  |  View Paper
Gastric suction for 1 h or ingestion of cimetidine reduced the plasma concentration of secretin by approx.
Regulatory Peptides  •  1983  |  View Paper
Therefore, the reduction of TLI response to injection of secretin may be tentatively attributed to the inhibition of gastric acid secretion and delivery to the duodenum caused by cimetidine.
Scandinavian journal of gastroenterology. Supplement  •  1980  |  View Paper
Plasma secretin levels were elevated for 6 postprandial hr, but were reduced by cimetidine as a result of marked suppression of acid secretion.
The Tohoku journal of experimental medicine  •  1984  |  View Paper
Intravenous administration of cimetidine , 150 mg, produced a marked suppression of postprandial increases in both pancreatic bicarbonate output and plasma secretin concentration.
The American journal of physiology  •  1979  |  View Paper