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Discover Supplement-Drug Interactions
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Last Updated: 2 years ago
drug:
Cimetidine
supplement:
Lactase
Research Papers that Mention the Interaction
“In vitro addition of cimetidine also produced significant inhibition of enzymes, the inhibition constant (Ki) for sucrase, lactase , maltase and alkaline phosphatase being 22.8, 4.5, 11.5 and 4.8 mM, respectively.”
“It was further observed that in vitro addition of cimetidine also decreased Vmax in case of maltase, sucrase and lactase , Km was unchanged, whereas in case of alkaline phosphatase there was a decrease in Vmax and increase in Km, as compared to the controls.”
Effect of cimetidine on intestinal absorption & digestive functions in mice.
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