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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
drug:
Cimetidine
supplement:
Iron, Dietary
Research Papers that Mention the Interaction
“ Cimetidine has a structure that would suggest strong binding to iron ions.”
Ferrous sulfate reduces cimetidine absorption“The results imply that cimetidine provides a neuroprotective effect by binding to iron and copper, thus making them unavailable for free radical production.”
“Moreover, the imidazole ring and cyanoguanidine group of cimetidine may play an important role in inhibition by binding to Fe in heme group and glutamic acid 51 residue on the enzyme, respectively.”
Effect of Cimetidine on Catalase Activity of Pseudomonas aeruginosa: A Suggested Mechanism of Action“Only cimetidine can apparently bind and inactivate iron , which further emphasizes its antioxidant capacity.”
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