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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
drug:
Cimetidine
supplement:
Intrinsic Factor
Research Papers that Mention the Interaction
“The suppressive effects of cimetidine on acid, pepsin, and intrinsic factor secretion have been well documented; however, the effect of cimetidine on cobalamin absorption has not been assessed.”
Malabsorption of protein-bound cobalamin but not unbound cobalamin during cimetidine administration“ Cimetidine (300 mg) completely inhibited acid, pepsin, and intrinsic factor concentration and output stimulated by betazole.”
“An H2 receptor antagonist, cimetidine , blocked the increases in IF secretion and tissue cAMP levels due to histamine, and the increase in IF secretion due to IBMX.”
Evidence for involvement of cyclic nucleotides in intrinsic factor secretion by isolated rabbit gastric mucosa.
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