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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
drug:
Cimetidine
supplement:
Heme Iron
Research Papers that Mention the Interaction
“ Cimetidine , which inhibits cytochrome … with the heme iron , significantly blocked iron release, whereas ranitidine, which has a similar structure as cimetidine but is a weak inhibitor of P-450, … effect (H2O2, 0.42 +/- 0.04; H2O2 + cimetidine, 0.23 +/- 0.02 nmol/mg protein; N = 4, P < 0.01).”
Role of cytochrome P-450 in hydrogen peroxide-induced cytotoxicity to LLC-PK1 cells.
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