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Last Updated: 3 years ago

Possible Interaction: Cimetidine and Cupric Cation

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drug:

Cimetidine

supplement:

Cupric Cation

Research Papers that Mention the Interaction

“ Cimetidine and its complexes with Cu(II) and Fe(III) ions inhibited ferricytochrome c and NBT reduction even when metal chelators were added to the reaction medium.”

Effects of cimetidine and its metal complexes on nitroblue tetrazolium and ferricytochrome c reduction by superoxide radicals.

General pharmacology • 1999 | View Paper

“At physiological pH values, low concentrations of Cu(II) complexes (0.025 mM) with Cim and CyHH could scavenge O2-, but high concentrations of these compexes (0.25 mM) yielded hydroxyl radicals (.OH) during dismutation of O2-.”

Generation of hydroxyl radicals during dismutation of superoxide by SOD model compounds.

Archives of biochemistry and biophysics • 1994 | View Paper

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