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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
drug:
Cimetidine
supplement:
Copper
Research Papers that Mention the Interaction
“The mediation of copper in the action of cimetidine on rheumatoid arthritis should thus be ruled out, the influence of the drug being rather interpretable in terms of reduction of histamine release.”
An assessment of the physiological significance of cimetidine interactions with copper and zinc in biofluids as based on the computer-simulated distribution of the involved complexes at therapeutic levels of the drug“The results imply that cimetidine provides a neuroprotective effect by binding to iron and copper , thus making them unavailable for free radical production.”
Cimetidine: antioxidant and metal‐binding properties“… Cu ,Zn‐SOD (superoxide radical scavenger) 60 000 units/kg, allopurinol (competitive … oxidase) 50 mg/kg, dmPGE2 (prostaglandin analogue) 10 μg/kg, cimetidine (H2‐receptor antagonist) 10 mg/kg or pirenzepine (selective antimuscarinic drug) 10 mg/… reduced the DDC‐induced (800 mg/kg) gastric antral ulcer formation in rats.”
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