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“The restriction of intracellular Ca overload by cilnidipine is of interest since intracellular Ca overload is closely associated with atrial fibrillation in patients [5].”
“ Cilnidipine is a dual blocker of L‐type voltage‐gated Ca2+ channels in vascular smooth muscle and N‐type Ca2+ channels in sympathetic nerve terminals that supply blood vessels.”
British journal of pharmacology • 2006 | View Paper
“This blockade of the N‐type Ca2+ channel , as well as the L‐type Ca2+ channel by cilnidipine suggests that it could be used therapeutically for treatment of hypersensitive sympathetic disorders associated with hypertension.”