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Discover Supplement-Drug Interactions

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Last Updated: 2 years ago

Possible Interaction: Chymotrypsin and Phenylalanine

supplement:

Chymotrypsin

supplement:

Phenylalanine

Research Papers that Mention the Interaction

Mutating two phenylalanines (FF174) in the vicinity of the prostasin cleavage site prevented proteolytic activation by chymotrypsin.
The Journal of general physiology  •  2012  |  View Paper
Lysolecithin or α-chymotrypsin increases the maximum velocity 20-fold, decreases the Km for phenylalanine by 50%, and converts the phenylalanine-saturation curve from the sigmoidal to the hyperbolic form.
The Journal of biological chemistry  •  1973  |  View Paper
In this work, two segmented polyurethaneureas containing L-phenylalanine residues in the chain extender and two control polymers were subjected to degradation in the presence of chymotrypsin.
Journal of biomaterials science. Polymer edition  •  2002  |  View Paper
The ethyl esters of l -tyrosine and phenylalanine and their acyl derivatives are rapidly hydrolyzed by chymotrypsin.
Biochimica et biophysica acta  •  1951  |  View Paper