Possible Interaction: Chymotrypsin and Penicillins

“ Chymotrypsin increased the kidney clearance of penicillin , methicillin, oxacillin, streptomycin and gentamycin by 1.7, 1.9, 2.2, 1.2 and 1.5 times respectively.”

“ Chymotrypsin may be of considerable value in the enhancement of penicillin penetration into reiatively inaccessible tissues, such as the brain and eye, thereby making it possible to eliminate penicillin-sensitive bacteria which have become localized in these areas.”