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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
supplement:
Chymotrypsin
drug:
Hydrochlorothiazide
Research Papers that Mention the Interaction
“… chymotrypsin … HCTZ , the Na/In ratio decreased from 36.8 ± 2.3% to 28.0 ± 3.4% (P < 0.05), whereas when given with amiloride, there … in the ratio (45.8 ± 3.4% versus 45.5 ± 2.3%), indicating that stimulation of sodium reabsorption by chymotrypsin was ENaC-dependent.”
Protease stimulation of renal sodium reabsorption in vivo by activation of the collecting duct epithelial sodium channel (ENaC).
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