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Discover Supplement-Drug Interactions

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Last Updated: 2 years ago

Possible Interaction: Chondroitin Sulfates and Nitric Oxide

Research Papers that Mention the Interaction

CS is also able to prevent the apoptosis of chondrocytes induced in vitro by nitric oxide.
Advances in pharmacology  •  2006  |  View Paper
Further experiments showed that CS could increase the secretion levels of NO , TNF-α, IL-6 and IL-10 via activating the corresponding mRNA expression in macrophages through the toll-like receptor 2 (TLR2).
Carbohydrate polymers  •  2018  |  View Paper
Finally, CS inhibited iNOS induction caused by OGD/Reox and thereby nitric oxide (NO) production measured as a reduction in DAF-2 DA fluorescence.
Neurochemistry International  •  2011  |  View Paper
Our results showed that CS inhibited TNF-alpha-induced NF-kappaB activation and subsequent vascular cell adhesion molecule 1 and inducible nitric oxide synthase expressions by blocking Akt signals in JB6 cells.
Cancer letters  •  2008  |  View Paper
Synthesis of NO was reduced with CS alone and the combination after 24h of culture.
Osteoarthritis and cartilage  •  2005  |  View Paper
Chondroitin sulfate and dermatan sulfate, although not stimulating the production of cytokines or of PGE2, elicited the production by macrophages of nitric oxide.
Journal of leukocyte biology  •  1999  |  View Paper