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Try: Ginkgo, Methotrexate, Glucosamine

Last Updated: 3 years ago

Possible Interaction: Chondroitin Sulfates and Hydroxyproline

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supplement:

Chondroitin Sulfates

supplement:

Hydroxyproline

Research Papers that Mention the Interaction

“ C-4S increased the cathepsin K-mediated release of hydroxyproline from insoluble type I collagen 10-fold but had only a less than 2-fold enhancing effect on the hydrolysis of intact cartilage.”

Collagenolytic activity of cathepsin K is specifically modulated by cartilage-resident chondroitin sulfates.

Biochemistry • 2000 | View Paper

“Labeled hydroxyproline increased by 132% in ligament cells, 27% in tenocytes and 49% in epitendon cells after a 48 h exposure to 5 μg ml−1 glcN + 4 μg ml−1 CS.”

Collagen Synthesis in Tenocytes, Ligament Cells and Chondrocytes Exposed to a Combination of Glucosamine HCl and Chondroitin Sulfate

Evidence-based Complementary and Alternative Medicine : eCAM • 2006 | View Paper

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