Allen Institute for Artificial Intelligence
supp.ai logo
supp.ai

Discover Supplement-Drug Interactions

Disclaimer: The information contained herein should NOT be used as a substitute for the advice of an appropriately qualified and licensed physician or other health care provider. The tool is not a substitute for the care provided… (more)
Last Updated: 3 years ago

Possible Interaction: Chondroitin Sulfates and Glucosamine Sulfate

Research Papers that Mention the Interaction

This assumption is not scientifically plausible for this study because CS plus GS treats symptoms, and therefore any benefits of treatment will not be retained after the treatment stops.
Arthritis & rheumatology  •  2017  |  View Paper
Similarly a combination of CS and GS was more effective in inhibiting MMP3 gene expression and secretion than the single components.
The inhibition of MMP3 secretion due to GS plus CS was accompanied by a decrease in TNF-α production.
Molecules  •  2009  |  View Paper
This was confirmed by the decreased resorptive activity for the combination of CS and GS.
Arthritis research & therapy  •  2007  |  View Paper
There is some evidence to suggest a structure-modifying effect of glucosamine sulfate and chondroitin sulfate.
Drugs & aging  •  2007  |  View Paper
The benefits of CS and GS in combination are more pronounced than those of CS alone.
The reduction of arthritic disease by CS plus GS is associated with a reduction of IL-1 β and MMP-9 synthesis.
Treatment with CS alone and CS plus GS inhibited the production of edema and prevented raised levels of joint MMP-9 associated with arthritis.
Treatment with CS plus GS , but not CS alone, significantly reduced clinical scores, incidences of disease, joint temperatures, and joint and serum IL-1β levels.
Experimental biology and medicine  •  2005  |  View Paper