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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
supplement:
Chondroitin Sulfates
drug:
Celecoxib
Research Papers that Mention the Interaction
“ResultsIn the adjusted mITT … treatment, patients treated with CS had a significant reduced … in the medial compartment ( celecoxib –8.1 % ± 4.2, CS –6.3 % ± 3.2; p = 0.018) and medial condyle (–7.….5 % ± 3.9; p = 0.008); no significant effect was seen in the lateral compartment.”
“…,CS reduced CVL … months ( celecoxib –5.6 % ± 3.0, CS –4.5 % ± 2.6; p = 0.049) and 24 months (celecoxib –8.4 % ± 4.2, CS –6.6 % ± …), and in the medial condyle at 24 months (celocoxib –8.1 % ± 4.7, CS –5.7 % ± 4.0; p = 0.010).”
Chondroitin sulfate efficacy versus celecoxib on knee osteoarthritis structural changes using magnetic resonance imaging: a 2-year multicentre exploratory study“Of the three drugs tested, only Celecoxib prevented the decrease of AGC mRNA and inhibited the release of CS.”
The influence of Celecoxib on matrix synthesis by chondrocytes under mechanical stress in vitro.
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