supp.ai
Discover Supplement-Drug Interactions
Disclaimer: The information contained herein should NOT be used as a substitute for the advice of an appropriately qualified and licensed physician or other health care provider. The tool is not a substitute for the care provided… (more)
Last Updated: 3 years ago
supplement:
Niacin
Research Papers that Mention the Interaction
“Inhibition of AChE activity leads to the accumulation of large amounts of acetylcholine and hyperactivity of the cholinergic system by stimulating acetylcholine receptors - muscarinic and nicotinic.”
[Today's threat of use of organophosphorus compounds].“While muscarinic autoreceptors inhibit ACh release, nicotinic autoreceptors enhance ACh release and thus disruption of these processes could potentially affect cholinergic toxicity following exposure to anticholinesterases.”
Nicotinic autoreceptor function in rat brain during maturation and aging: possible differential sensitivity to organophosphorus anticholinesterases.“DFP and other cholinesterase inhibitors convert muscarinic effects to small doses of benzoylcholine into nicotinic effects and potentiate nicotinic effects of the larger doses.”
Correlation between pharmacological responses to benzoylcholine, methacholine and acetylcholine and activity of cholinesterases.
Help us improve supp.ai, we'd love to hear your feedback: Submit Feedback