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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
supplement:
Choline
supplement:
Vitamin B 6
Research Papers that Mention the Interaction
“Conclusion: The inverse associations between choline and vitamin B6 and the risk of hepatocellular carcinoma development are novel and warrant further investigation.”
Prediagnostic Levels of Serum One-Carbon Metabolites and Risk of Hepatocellular Carcinoma“There were significant relationships between vitamin B6 and N-acetylaspartate (NAA), choline , and creatine, as well as between vitamin B12 and creatine (ps < 0.05), whereas NAA in the PCC increased, albeit not significantly (p > 0.05).”
“ Vitamins B6 , B12 and folate can enhance methylation capacity and therefore could influence choline availability not only by increasing endogenous choline synthesis but also by reducing choline utilisation.”
Plasma choline concentration varies with different dietary levels of vitamins B6, B12 and folic acid in rats maintained on choline-adequate diets“Moreover, the growth response to a combination of choline + pyridoxine ( PN ) was also greater than that obtained from any of the three nutrients fed alone; even PN + riboflavin (in the absence of choline) produced responses greater than those observed with the unsupplemented negative-control diet.”
“c) PLP decreases the cellular uptake of choline.”
Effect of pyridoxal 5'-phosphate and valproic acid on phospholipid synthesis in neuroblastoma NA.“Addition of vitamin B6 has an aggravating influence on the specific effect of deficiency of choline , especially with regard to the development of cortical necrosis of the kidneys.”
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