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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
Research Papers that Mention the Interaction
“In addition, several cationic drugs such as diphenhydramine and verapamil competitively inhibited choline uptake in TR-TBT 18d-1 with K(i) of 115microM and 55microM, respectively.”
Choline transport via choline transporter-like protein 1 in conditionally immortalized rat syncytiotrophoblast cell lines TR-TBT.“Additionally, two typical p-glycoprotein substrates, daunomycin and verapamil , both inhibited choline accumulation.”
“Several commonly prescribed pharmaceuticals known to cross the placental barrier including imipramine, verapamil , propranolol, quinine, flurazepam, amiloride and ritodrin were observed to inhibit conductive choline uptake suggesting an interaction with the mechanism mediating conductive choline transport.”
“ Verapamil and its analogue D-600 have been found to inhibit the uptake of serotonin, dopamine, norepinephrine and choline into rat forebrain synaptosomes.”
Inhibition of high affinity synaptosomal uptake systems by verapamil.
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