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Discover Supplement-Drug Interactions

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Last Updated: 3 years ago

Possible Interaction: Choline and Serine

supplement:

Choline

supplement:

Serine

Research Papers that Mention the Interaction

The exchange of choline for serine in these compounds results in the loss of this type of antitumour specificity.
Anticancer research  •  1992  |  View Paper
Maximal incorporation of choline occurs at 1.6 to 3.3·10−3M concentration of calcium ions and a pH value of 9.0 d- and l-serine competitively inhibit this reaction.
Biochimica et biophysica acta  •  1961  |  View Paper
By using equimolar concentrations of PC and sodium dodecyl sulphate (1 mM to 5 mM), the Michaelis constant (Km) was estimated to be 1.74 mM. Addition of choline and serine at 10 mM concentration reduced phospholipase D activity by 31% and 22%, respectively.
Lipids  •  2006  |  View Paper
It was found that inclusion of 1 mm choline in the growth media greatly lowered the rate of labeling of the methylated phospholipids by methionine and serine ; sterol labeling was unaffected.
The Journal of biological chemistry  •  1969  |  View Paper