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“Since choline uptake may play a critical role in PC production and lung surfactant homeostasis for normal breathing, it is of interest to characterize transporters controlling the disposition of choline in ATII cells.”
Biological & pharmaceutical bulletin • 2010 | View Paper
“Maturational development of phosphatidyl choline is reflected in an increase in the concentration of this surfactant , particularly in lamellar bodies, and possibly in remodeling of fatty acid composition in both lamellar bodies and microsomes.”
“Intratracheal injection of 3-day-old rabbits with radioactively labeled palmitic acid and choline results in an 8-10-fold increase in the efficiency of their incorporation into surfactant phosphatidylcholine when compared to the intravenous injection of these precursors.”