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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
supplement:
Choline
drug:
Propranolol
Research Papers that Mention the Interaction
“Several commonly prescribed pharmaceuticals known to cross the placental barrier including imipramine, verapamil, propranolol , quinine, flurazepam, amiloride and ritodrin were observed to inhibit conductive choline uptake suggesting an interaction with the mechanism mediating conductive choline transport.”
Choline transport in human placental brush-border membrane vesicles.“Utilizing platelets whose phospholipids were … that local anesthetics, chlorpromazine and propranolol block: (a) formation of 14C-thromboxane B2, 14C-prostaglandins and 14C-hydroxyacids (12-L-hydroxy-5,8,10,14-… (phospholipid) 14C-archidonate; and (b) block the fall in the 14C-arachidonate content of platelet phospholipids, especially phosphatidyl choline.”
“It is shown that, in the presence of dl-propranolol , incorporation of 32P into choline and ethanolamine phospholipids is markedly reduced, whereas an increase of label in phosphatidylglycerol is observed.”
Separation and analysis of 32P-labeled phospholipids by a simple and rapid thin-layer chromatographic procedure and its application to cultured neuroblastoma cells.
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