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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
supplement:
Choline
drug:
Norepinephrine
Research Papers that Mention the Interaction
“administration of CDP-choline or its cholinergic metabolites phosphocholine and choline increases plasma adrenaline and noradrenaline concentrations by enhancing nicotinic cholinergic neurotransmission in the sympatho-adrenal system.”
“ choline (1.5 mumol)-induced elevations in plasma adrenaline and noradrenaline.”
“injection of choline (0.5-1.5 mumol) also increased plasma adrenaline and noradrenaline dose- and time-dependently.”
Peripheral administration of CDP-choline, phosphocholine or choline increases plasma adrenaline and noradrenaline concentrations.“ Urinary norepinephrine levels also increased on days that the animals received choline.”
“Compared with control animals, rats administered total parenteral nutrition plus choline for 5 days showed a decrease of approximately 5- and 2-fold in urinary dopamine and norepinephrine concentration, respectively.”
“4 Noradrenaline (10−6−10−4 m) evoked a concentration‐dependent increase in the levels of choline and choline phosphate, but not in those of glycerophosphocholine, in the rabbit saphenous artery.”
“ Norepinephrine and the phorbol ester, phorbol myristate acetate (PMA), increased the formation of choline and phosphorylcholine in rat aorta.”
“ Norepinephrine stimulated the high affinity choline transport process but not the low and the magnitude of its stimulation in 3 different brain regions was correlated with the choline acetyltransferase activity of those regions.”
“ Choline augmented the duration and amplitude of noradrenaline‐induced tonic contraction and final contractile oscillations.”
Messenger molecules of the phospholipase signaling system have dual effects on vascular smooth muscle contraction
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