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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
supplement:
Choline
drug:
Neostigmine
Research Papers that Mention the Interaction
“Also, choline (100 microM) reduced the maximum response to ACh in the presence of neostigmine and that to CCh to 60-80% of control.”
A study of the contractile response to acetylcholine in human ileal and detrusor muscle: origin of the low efficacy of acetylcholine.“ Ch administration significantly increased ACh release (to 136% of basal values; P < 0.01) in the presence of the low neostigmine concentration, but failed to significantly increase ACh release following local electrical depolarization of striatal neurons.”
“ Ch administration significantly increased microdialysate Ch levels in the presence of both of the neostigmine concentrations.”
Effect of choline on basal and stimulated acetylcholine release: an in vivo microdialysis study using a low neostigmine concentration“4 Tubocurarine, choline and hexamethonium significantly decreased the endplate depolarization induced by repetitive nerve stimulation in the presence of neostigmine.”
“run‐down caused by choline or hexamethonium, but not that induced by tubocurarine, was reciprocally reversed by neostigmine.”
“It was found that under the effect of prozerin the specific activity of choline lowers only in the muscles and nicotinic acid evokes its decrease in the liver and muscles.”
“The enzyme activity was maximal against acetyl esters of choline and was inhibited by neostigmine.”
Partial purification and some properties of a cholinesterase from bush bean (Phaseolus vulgaris L.) roots.
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