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Discover Supplement-Drug Interactions

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Last Updated: 3 months ago

Possible Interaction: Choline and Miltefosine

supplement:

Choline

Research Papers that Mention the Interaction

HexPC inhibited the incorporation of choline into phosphatidylcholine and the pattern of accumulation of soluble choline-derived metabolites pinpointed CTP:phosphocholine cytidylyltransferase (CT) as the inhibited step in vivo.
Biochimica et biophysica acta  •  1998  |  View Paper
HePC substantially inhibited the membrane uptake of inositol and of choline in KB and Raji.
European journal of cancer  •  1995  |  View Paper
In further experiments, we demonstrated that HePC inhibited the incorporation of radiolabeled choline into phosphatidylcholine and at a later time point into sphingomyelin.
The Journal of Biological Chemistry  •  1998  |  View Paper
Finally, we have demonstrated using inhibition studies with choline analogs that miltefosine and octadecyltrimethylammonium bromide are potent inhibitors of this metabolic pathway.
Molecular and biochemical parasitology  •  2014  |  View Paper