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Last Updated: 3 years ago

Possible Interaction: Choline and Memantine

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supplement:

Choline

drug:

Memantine

Research Papers that Mention the Interaction

“Simultaneously, MEM also reduced the apoptosis of choline acetyl transferase-immunoreactive cholinergic amacrine cells within the RGC layer of AD mice.”

Neuroprotective effect of memantine on the retinal ganglion cells of APPswe/PS1ΔE9 mice and its immunomodulatory mechanisms.

Experimental eye research • 2015 | View Paper

“ Memantine caused a concentration-dependent reduction of the amplitudes of whole-cell currents evoked by the alpha7(*) nAChR-selective agonist choline (10 mM) or by N-methyl-d-aspartate (NMDA) (50 muM) plus glycine (10 muM).”

Memantine blocks alpha7* nicotinic acetylcholine receptors more potently than n-methyl-D-aspartate receptors in rat hippocampal neurons.

The Journal of pharmacology and experimental therapeutics • 2005 | View Paper

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