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Discover Supplement-Drug Interactions

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Last Updated: 5 months ago

Possible Interaction: Choline and Memantine

supplement:

Choline

Research Papers that Mention the Interaction

Simultaneously, MEM also reduced the apoptosis of choline acetyl transferase-immunoreactive cholinergic amacrine cells within the RGC layer of AD mice.
Experimental eye research  •  2015  |  View Paper
Memantine caused a concentration-dependent reduction of the amplitudes of whole-cell currents evoked by the alpha7(*) nAChR-selective agonist choline (10 mM) or by N-methyl-d-aspartate (NMDA) (50 muM) plus glycine (10 muM).
The Journal of pharmacology and experimental therapeutics  •  2005  |  View Paper
Intraperitoneal injection of NGP1-01 (40 mg/kg) reduced NMDA-induced membrane breakdown by 31% (P<0.01) while memantine (10 mg/kg) reduced choline release by 40%.
Neurochemical Research  •  2005  |  View Paper