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Last Updated: 3 months ago

Possible Interaction: Choline and Mecamylamine



Research Papers that Mention the Interaction

Blood pressure responses to choline (150 µg) were attenuated by pretreatment with both mecamylamine and atropine.
Clinical and experimental pharmacology & physiology  •  2008  |  View Paper
In cultured superior cervical … and rat, choline (0.1-30 mM)-evoked … by 1-30 microM mecamylamine , 1-30 microM methyllycaconitine, 10-300 nM alpha-bungarotoxin, and 0.1-10 microM desipramine and … the presence of similar functional alpha7-nAChRs in cerebral perivascular sympathetic neurons of pigs and rats.
American journal of physiology. Heart and circulatory physiology  •  2006  |  View Paper
The LTPn induced by epibatidine at 3.0 mug/kg or choline at 30 mg/kg was significantly suppressed by pre-treatment but not post-treatment with mecamylamine (0.5 mg/kg, i.p.),
Journal of pharmacological sciences  •  2003  |  View Paper
choline (150 microg) was inhibited by pretreatment with the nicotinic receptor antagonist, mecamylamine (50 microg; i.c.v.),
Brain Research  •  2002  |  View Paper
The rat's exploratory behaviour tended to be attenuated by central administration of hemicholinium (a choline uptake blocker), and it was significantly inhibited by mecamylamine (a nicotinic receptor antagonist), and pirenzepine (a selective M1 receptor antagonist).
Journal of Neural Transmission  •  2000  |  View Paper
blocked the hypothermic effect of choline (150 microg), but the response was only partially attenuated by pre-treatment with the nicotinic receptor antagonist, mecamylamine (20 microg, i.c.v.).
European journal of pharmacology  •  1998  |  View Paper
Mecamylamine abolished vasopressin response to endotoxin as well as to choline.
Journal of cardiovascular pharmacology  •  1997  |  View Paper
Pretreatment of rats with mecamylamine (50 micrograms; intracerebroventricularly), the nicotinic receptor antagonist, completely inhibited the ACTH and beta-endorphin response to choline (150 micrograms; intracerebroventricularly).
European journal of pharmacology  •  1996  |  View Paper